Yang Liu, MD, PhD

Profile

Yang Liu received her M.D. in Ophthalmology at Jilin University in China in 2003. In 2007, she obtained her Ph.D. from Yamaguchi University Graduate School of Medicine in Japan, studying corneal wound healing and inflammation. Following completion of her Ph.D., Yang Liu joined in Gerhardinger Laboratory at the Schepens Eye Research Institute, focusing on the role of inflammatory cytokines in the pathogenesis of diabetic retinopathy.

Education

2007     Ph.D. in Ophthalmology, Yamaguchi University Graduate School of Medicine,  Yamaguchi, Japan

2003     M.D. in Ophthalmology, Jilin University, Jilin, China     

Postdoctoral Training

2007 –   Research Fellow, Schepens Eye Research Institute and Harvard Medical  School, Boston, MA

Research Project

The role of IL-1beta in the pathogenesis of diabetic retinopathy

Publications

1. Liu Y, Kimura K, Yanai R, Chikama T, Nishida T. Cytokine, chemokine, and adhesion molecule expression mediated by mitogen-activated protein kinases in human corneal fibroblasts exposed to poly(I:C). Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3336-44

2. Liu Y, Ko JA, Yanai R, Kimura K, Sagara T, Chikama T, Nishida T. Induction by latanoprost of collagen gel contraction mediated by human Tenon fibroblasts: role of intracellular signaling molecules. Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1429-36 (cover paper)

3. Morishige N, Ko JA, Liu Y, Chikama T , Nishida T : Localization of Semaphorin 3A in the rat cornea : Exp Eye Res. 2008 Apr;86(4):669-74.

4. Chikama T, Liu CY, Mejij J, Hayashi Y, Wang IJ, Liu Y, Nishida T, and Kao WW. Excess FGF-7 in Corneal Epithelium Causes Anomaly: Corneal Intraepithelial Neoplasia in Young and Epithelium Hyperplasia in Adult Mice. Am J Pathol. 2008 Mar;172(3):638-49.

5. Yanai R, Liu Y, Ko JA, Nishida T. Effects of ambient oxygen concentration on the proliferation and viability of cultured human corneal epithelial cells. Exp Eye Res. 2008 Feb;86(2):412-8.

6. Ko JA, Liu Y, Yanai R, Chikama T, Takezawa T, Nishida T. Upregulation of tight-junctional proteins in corneal epithelial cells by corneal fibroblasts in collagen vitrigel cultures. Invest Ophthalmol Vis Sci. 2008 Jan;49(1):113-9.

7. Chikama T, Wakuta M, Liu Y, Nishida T. Deviated mechanism of wound healing in diabetic corneas. Cornea. 2007 Oct;26(9 Suppl 1):S75-81.

8. Liu Y, Yanai R, Lu Y, Hirano S, Sagara T and Nishida T. Effects of anti-glaucoma drugs on collagen gel contraction mediated by human corneal fibroblasts. J Glaucoma. 2006 Jun; 15(3):255-9.

9. Liu Y, Yanai R, Lu Y, Kimura K, and Nishida T. Promotion by fibronectin of collagen gel contraction mediated by human corneal fibroblasts. Exp Eye Res. 2006 Nov; 83(5):1196-204.

10. Lu Y, Liu Y, Fukuda K, Nakamura Y, Kumagai N, Nishida T. Inhibition by triptolide of chemokine, proinflammatory cytokine, and adhesion molecule expression induced by lipopolysaccharide in corneal fibroblasts. Invest Ophthalmol Vis Sci. 2006 Sep; 47(9):3796-800.

11. Lu Y, Fukuda K, Liu Y, Kumagai N, and Nishida T. Dexamethasone inhibition of IL-1–induced collagen degradation by corneal fibroblasts in three-dimensional culture. Invest Ophthalmol Vis Sci. 2004 Sep; 45(9):2998-3004.